Research studies

Medipal is an efficient and powerful support in clinical studies.

Medipal is a efficient and powerful support that is used in clinical studies and several scientific studies have been conducted. By using the participant’s mobile phone as a tool, compliance is improved due to the rapid communication. The basic data also gets improved because the responses are in real time when you study effects, side effects, behavioural patterns, trends or other things. The answers can form time series data, which are observations over time of the same variable.

Please read more about the studies below.

Clinical studies and reports where Medipal has been used

Daily assessments of perceived sensations in obese and non-obese children/adolescents using a new mobile application. (Oral Presentation 11) November 2017

by M.Dahlbom1,2, M.Lidström1, H.Vilen1, K.Andersson1, I.Ciba1,2, D Kritikos1,2, and A.Forslund1,2
1) Uppsala University Children´s Hospital, Uppsala, Sweden
2) Department of Women’s and Children’s Health, Uppsala University, Uppsala, Sweden

Conclusion: Preliminary, there are differences in perceived sensations for hunger, wellbeing, stress, tiredness and sleep duration between obese and non-obese children and adolescents. Medipal® provides a new tool which can be used daily for different purposes in the treatment of obese children as well as non-obese children.

Tools that show you how to feel between care visits. November 2016


Summary: Digitalisation does not necessarily entail transformative changes in processes. There are tools that are relatively easily adapted to existing ways of working. One example is mobile, interactive Documentation plat forms that makes it easier to follow up patients ‘ conditions between different patients, revisits or medication. Data is collected by being questions asked by the care holder via the mobile phone and the patients’ responses are updated in real time in transparent graphs or other appropriate compilations.

At-home monitoring after surgery/anaesthesia – a challenge. March 2016

by Margareta Warren-Stomberg MD,1 Jan Jacobsson MD,2 Metha Brattwall PhD MD3 and Pether Jildenstål PhD1,4
1) Associate professor Senior Lecturer, Institute of Health and Care Sciences, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
2) Adjunct Professor, Anaesthesia & Intensive Care, Institution for Clinical Science, Karolinska Institutet, Danderyds University Hospital, Stockholm, Sweden
3) Doctor, Sahlgrenska University Hospital, Anesthesiology and Intensive Care, Unit of Daysurgery, Mölndal Gothenburg, Sweden
4) Senior Lecturer, Sahlgrenska University Hospital, Department of Anesthesia, Surgery and Intensive Care, Gothenburg, Sweden

Conclusion: Bringing telemedicine into follow-up after surgery/anaesthesia is requested, and furthermore, the feasibility study on day surgery presented here shows that it is technically easy to performand will provide robust information. It should be noted that further studies are needed in order to !nd better patient cooperation.

Mobile Phone-Based Quesionnaire for Assessing 3 months Modified Ranking Score After Acute Stroke – a pilot study. Oktober 2015

by Charith Cooray, MD; Marius Matusevicius; Nils Wahlgren, MD, PhD; and Niaz Ahmed, MD, PhD

Conclusion: Mobile phone–based automatic assessments of mRS performed well in comparison with clinical visit mRS and could be used as an alternative in stroke follow-up.

The Project InnoCent on improving benefits for distance care for young diabetics in 2015 at Uppsala University Hospital

by Annika Remaeus, project manager and head of Academic Innovation of the Uppsala University Hospital

Conclusion: For the InnoCent project it was optimal to use Medipal because it was already clear and CE-marked in order to be able to efficiently and digitally follow patients in their everyday life. Via Medipal we were able to send our own predetermined questions to the patients and also adapt them individually, which was important for our follow-up. We in the healthcare also got access to a new platform to capture events in the patients’ daily lives between the scheduled meetings. For effective care today, it is important to take advantage of the technical development that takes place/happened around us and to access and use digital and patient-safe tools that are already available, such as Medipal. (in Swedish)

Press release, 17 April 2014  (in Swedish)

Report on the use of Medipal at the Gastro Clinic, Danderyd Hospital. April 2013

By Susanna Jäghult, registered nurse, MD, Anna Nordström registered nurse
The Clinic of Gastro, Danderyd Hospital AB

Results: Patients, who were followed with Medipal, experienced better care compared to those that were followed in the usual way. Patients also expressed that Medipal was easy to use and wanted to continue using it after completing the study. Patients who were followed in this way had more frequent contacts with the health care, which is something that is pursued primarily in the treatment of adalimumab. (in Swedish)

A retrospective study based on electronic patient diaries and review of prophylactic treatment of migraines at the Neurounit Utsikten in Stockholm. July 2013

by Shanna Jalal. Supervisor: Christian Carlström, Martin Burman
Degree project in pharmacy 30 ECTS CR. Umeå University

Results: This study has shown that there is a statistically significant correlation between the frequency of migraine and the average daily temperature. With an increase in temperature the frequency of migraine is reduced. No correlation could be detected between frequency of migraine and atmospheric pressure. And no correlation could be found for other weather parameters. Changes in the temperature between the day of attack and the previous day had no effect on frequency of migraine. However, changes in air pressure from the day before the attack affected the frequency of migraine in a statistically significant way. This gives more understanding of the patients’ reports. By taking into account the intensity of the attacks and conducting a more patient specific study, the relationship between migraines and weather changes can be further strengthened.

Health Information: What Can Mobile Phone Assessments Add? Fall 2012

by Margareta Warrén Stomberg, RNA, PhD; Birgitta Platon, RNA; Annette Widén, RN; Ingegerd Wallner, RN; and Ove Karlsson, MD

Conclusion: The mobile phone system was found to provide a fast and safe basis for reporting pain postoperatively in real time. The results indicate that on days 3 and 4 the mobile phone group reported significantly higher levels of pain than the control group, and the cholecystectomy patients reported significantly more pain at movement on days 3 and 4 than the hysterectomy patients.

The mobile phone approach is an adaptation to modern technology and the mobility of individuals. This technology is user friendly and requires minimal support. However, as the sample size was small (n = 37), further studies are needed before additional conclusions can be drawn.

Estimation of Physical Activity Levels Using Cell Phone Questionnaires: A Comparison With Accelerometry for Evaluation of Between-Subject and Within-Subject Variations. September 2011

by Christin Bexelius PhD1, Sven Sandin MSc1, Ylva Trolle Lagerros MD PhD3, Jan-Eric Litton PhD1, MarieLöf PhD1,2,4
1) Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
2) Department of Clinical and Experimental Medicine, Linkoping University, Linkoping, Sweden
3) Unit of Clinical Epidemiology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
4) Corresponding author: Department of Medical Epidemiology and Biostatistics, Karolinska Institutet

Conclusions: Both the cell phone questionnaire and the accelerometer showed high within-subject variations. Furthermore, day-to-day variations in PAL within subjects assessed using the cell phone agreed well with corresponding accelerometer values. Consequently, our cell phone questionnaire is a promising tool for assessing levels of physical activity. The tool may be useful for large-scale prospective studies.

Is It Reliable To Use Cellular Phones for Symptom Assessment in Palliative Care? Report on a Study in Patients with Advanced Cancer. December, 2010

av Staffan Lundström, palliativa sektionen, Stockholms Sjukhem

Conclusion: Five hundred and twenty pairs of recorded data were obtained and there was no statistically significant difference between the two estimation methods. The patients thought that the mobile phone application was easy to use.

Measures of Physical Activity Using Cell Phones: Validation Using Criterion Methods. Januari 2010

Christin Bexelius1, MSc; Marie Löf1,2, PhD; Sven Sandin1, MSc; Ylva Trolle Lagerros3, MD PhD; Elisabet Forsum2, PhD; Jan-Eric Litton1, PhD
1)Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
2)Department of Clinical and Experimental Medicine, Faculty of Health Science, Linköping University, Linköping, Sweden
3)Clinical Epidemiology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden

Conclusions: A Java-based physical activity questionnaire administered daily using cell phones produced PAL estimates that agreed well with PAL reference values. Furthermore, the limits of agreement between PAL obtained using cell phones, and reference values were narrower than for corresponding estimates obtained using paper questionnaires. Java-based questionnaires downloaded onto cell phones may be a feasible and cost-effective method of data collection for large-scale prospective studies of physical activity.